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Multi-objective (MO) optimization problems require simultaneously optimizing two or more objective functions. An MO algorithm needs to find solutions that reach different optimal balances of the objective functions, i.e., optimal Pareto front, therefore, high dimensionality of the solution space can hurt MO optimization much severer than single-objective optimization, which was little addressed in previous studies. This paper proposes a general, theoretically-grounded yet simple approach ReMO, which can scale current derivative-free MO algorithms to the high-dimensional non-convex MO functions with low effective dimensions, using random embedding. We prove the conditions under which an MO function has a low effective dimension, and for such functions, we prove that ReMO possesses the desirable properties of optimal Pareto front preservation, time complexity reduction, and rotation perturbation invariance. Experimental results indicate that ReMO is effective for optimizing the high-dimensional MO functions with low effective dimensions, and is even effective for the high-dimensional MO functions where all dimensions are effective but most only have a small and bounded effect on the function value.