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Direct Preference Optimization (DPO) has emerged as a promising framework for aligning Large Language Models (LLMs) with human preferences by directly optimizing the log-likelihood difference between chosen and rejected responses. However, existing methods assign equal importance to all tokens in the response, while humans focus on more meaningful parts. This leads to suboptimal preference optimization, as irrelevant or noisy tokens disproportionately influence DPO loss. To address this limitation, we propose Optimal Transport-based token weighting scheme for enhancing direct Preference Optimization (OTPO). By emphasizing semantically meaningful token pairs and de-emphasizing less relevant ones, our method introduces a context-aware token weighting scheme that yields a more contrastive reward difference estimate. This adaptive weighting enhances reward stability, improves interpretability, and ensures that preference optimization focuses on meaningful differences between responses. Extensive experiments have validated OTPO’s effectiveness in improving instruction-following ability across various settings.