Total: 1
AI and population health are becoming increasingly intertwined, driven by the growing availability of multimodal data and rapid advances in AI. At the AAAI-26 New Faculty Highlights, I present our efforts to harness these trends to enhance our capacity to model, simulate, and adapt to complex dynamical processes. I first introduce our robust deep learning architectures for real-time outbreak response, highlighting how our frameworks capture uncertainty and dynamics across shifting distributions, multimodal data, hierarchical structures, and relational dependencies. I will then introduce our hybrid approaches that integrate machine learning with science-based mechanistic epidemiological models, including physics-informed neural networks, expert-guided generative models for causal inference, and differentiable agent-based models. Together, these advances illustrate how combining data-driven AI with domain knowledge can enable more reliable, adaptive, and actionable solutions to inform decision making in population health.